Trelegy changed my life.

Just wanted to put this out there. I have been trying to solve my worsening asthma symptoms for just over 5 years now. In winter of 2015 I developed a chest cough that lasted 8 months. Finally solved it by aggressively treating my allergies as it was caused by incessant post-nasal drip.

But my asthma was still bothering me every day after that. Went to a pulmonologist for the first time in my life and tried Advair (all strengths), Breo, QVAR (which helped the least by far), Symbicort, and Dulera. I ended up sticking with Dulera for the past 3 years (200mcg, 2 puffs twice a day). For the past 3 years my daily regimen of medication has been Dulera, Azelastine, Allegra, Singulair, and occasionally Flonase. On top of all that I was still needing to use my rescue inhaler at least once a day.

Long story short, my insurance switched over and I was forced to find another maintenance inhaler. Pulm prescribed Trelegy as it was recently approved to treat asthma, and holy fucking shit. I can finally breathe during the day consistently. Only times I ever need my rescue inhaler now are when I exercise, spend time around concentrated triggers, or when my GERD acts up.

My lungs seriously haven't felt this open since I was a kid. I also started double-dosing Flonase (at my pulmonologists request) and my post-nasal drip has finally almost completely disappeared. Now all I take is Trelegy once a day, Singulair and night, and Flonase twice a day.

If you have the opportunity to switch to Trelegy, I highly HIGHLY recommend it as someone who has struggled with asthma every single day for most of my life.

edit: I should add that I am 5 days in and the only side effects I have experienced are a slightly elevated heart rate for about 45 minutes or so after I take it and mild headaches occasionally that last for 5-10 mins.

edit 2: 1 month later since people are still replying, I had to stop taking it because I was allergic to the anticholinergic. My chest and neck started getting extremely itchy about 2 weeks into taking it. After stopping the Trelegy, the rash went away. Just to make sure it was the Trelegy and not another medication I had started at the time, I tried it again for about a week before the rash came back. I went back to Breo which is 2 out of the 3 meds in Trelegy and this still controls my asthma better than Dulera after consistent use, but it is nowhere near as great as Trelegy felt. Good luck to everyone trying it, I'm sure I'm just an outlier here!