Tips for first (and only) playthrough

I'm about to start Baldur's Gate 3 for the first time. The game is so vast and complex that I want to enjoy it as much as possible, but due to time constraints, I don't think I'll be able to play it more than once. At the same time, I don't want to rely on detailed guides—I want to go in as blind as possible.

What advice (without spoilers) would you give to have the best experience in a first playthrough?

For example: Should I commit to a specific role, or is it more fun to play as randomly as possible? Is there any game mechanic or specific build that's considered higher quality/more fun than others? That kind of thing.

Thanks in advance for your responses ❤️