Progesterone androgenic effect mitigation
Its pretty well known that negative effects from prog are fairly common in mtfs but seemingly nobody has a good answer for how to mitigate them. there are posts on this subreddit complaining that dutasteride has not solved their prog woes, and i imagine that if it was usually effective it itd be community knowledge that prog is best paired with duta.
If powers' mention of abnormal enzymatic metabolisation from rectal is the issue then i dont imagine oral would help, nor gel. progestins that arent awful are hard to acquire, and prog seems too helpful to ignore.
My personal experience is that rectal prog in any dose results in acne and hair loss in a fairly short amount of time regardless of bicalutamide or topical duta usage. scrotal spray between 12 and 60mg similarly poor effects. i also get none of the supposed nice things from prog like er, the bedroom benefits. i have however had those twice from CPA at about 1 month from discontinueing it, oddly. CPA in general seemed to be rather nice for intimacy things.
Does anyone know of anything interesting on this, or have anything they can suggest for prog issues?