What is your 'last resort' medication?

Like the pain is too mcuh to deal with. And you've tried many things that day. May be tried exercise, lying down, some over thr counter stuff but you're still in agony.

What is your last resort medication that's a little strong but you take to just get through the day/night? (Other than opioids )

Mine is etoricoxib. I also have a strip of ibuprofen but I've only ever taken 1