Missy

"Mom was a mess, Missy was a dumb teenager I had to look after both of them"

During a time before everyone had a cellphone when Sheldon was there, Missy at least had him to talk to even if he didn't always get it or understand. Her dad is gone and Georgie is busy with raising a child and providing for his new family. And Mary can't have a conversation without bringing up God. And even Paige Is gone in god knows where. And after the tornado Meemaw moved in with Dale so she probably doesn't see her as much anymore either.

I can only imagine how hard it must be for her. Everything and everyone she had but didn't appreciate is all gone now