Is it ever appropriate to follow up on an application if you haven’t heard anything?

I emailed a resume and cover letter to the person specified in the job listing, but I never got a confirmation that she received it. This was Monday (1/6). I also submitted an application on Indeed last Friday (1/3) before I saw that the posting on the org’s website asks for a cover letter and resume to be emailed.

Would it be a faux pas to email and make sure she received my documents? I’m going crazy at my current job and I need OUT.