Plugins Un-ticking themselves

Hey yall, quick question that I’m sure had a super simple answer/reason. Whenever I close out Starfield, some of the plugins on MO2, usually the SFBG003/4/5/6/7/8 plugins (or something similar, I’m not home so I can’t check) end up unticking themselves. Are they still active in game when I check them again and start the game? Why do they always untick themselves?